1333204-25-3

Basic information

• Product Name: C₄₀H₃₈N₄
• Synonyms: C₄₀H₃₈N₄
• CAS NO: 1333204-25-3
• Molecular Weight: 574.769
• Mol File: 1333204-25-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₀H₃₈N₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₃₈N₄(1333204-25-3)
• EPA Substance Registry System: C₄₀H₃₈N₄(1333204-25-3)

Safety Data

• Hazardous Substances Data: 1333204-25-3(Hazardous Substances Data)

Upstream product

• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 180740-69-6 5-tert-butylbenzene-1,3-dicarbaldehyde 
• 16308-65-9 dimethyl 5-(tert-butyl)isophthalate 
• 2359-09-3 5-t-butylisophthalic acid 

Relevant articles and documents

Pincer iridium(III)-catalyzed enantioselective C(sp3)-H functionalization via carbenoid C[sbnd]H insertion of 3-diazooxindoles with 1,4-cyclohexadiene

The asymmetric carbenoid C[sbnd]H insertion of 3-diazooxindoles into 1,4-cyclohexadiene has been accomplished in the presence of chiral bis(imidazoline) NCN pincer iridium(III) complexes as the catalysts. With a catalyst loading of 0.5 mol%, the reactions proceeded smoothly at 0 °C to afford a variety of chiral 3-substituted oxindoles in good yields with moderate to excellent enantioselectivities (up to 99% ee). The protocol exhibits good functional group tolerance with respect to 3-diazooxindoles and is readily scaled up to 2 mmol scale without any loss in activity and enantioselectivity. Density functional theory (DFT) calculations have been performed to better understand the reaction mechanism and to explain the stereochemical outcome of the reactions.