1333231-50-7

Upstream product

• 1385184-01-9 C₈H₁₄N₂O₃*ClH 
• 1333231-44-9 benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl)amino)pentan-2-yl)carbamate 
• 1333231-43-8 C₂₁H₃₁N₃O₅ 
• 1350624-56-4 C₂₅H₃₈N₄O₆ 
• 1350624-48-4 C₂₂H₃₁N₃O₆ 
• 1350624-45-1 C₁₃H₂₂N₂O₅ 

Relevant academic research and scientific papers

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles

Series of structurally-diverse α-ketoamides and α- ketoheterocycles was synthesized and subsequently investigated for inhibitory activity against Norwalk virus 3C protease in vitro, as well as anti-norovirus activity in a cell-based replicon system.

Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease

The first series of peptidyl aldehyde inhibitors that incorporate in their structure a glutamine surrogate has been designed and synthesized based on the known substrate specificity of Norwalk virus 3C protease. The inhibitory activity of the compounds wi