1333236-35-3

Upstream product

• 1240382-69-7 (E)-5-(2-iodovinyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 1240382-67-5 (E)-2,2-dimethyl-5-(2-(trimethylsilyl)vinyl)-4H-benzo[d][1,3]dioxin-4-one 
• 1333235-99-6 (3S,4S,Z)-4-(methoxymethoxy)oct-5-en-7-yne-1,3-diol 
• 1333235-41-8 (5S,6S)-5-((Z)-but-1-en-3-ynyl)-11,11-dimethyl-10,10-diphenyl-2,4,9-trioxa-10-siladodecan-6-ol 
• 1333235-35-0 (5S,6S)-5-((Z)-but-1-en-3-ynyl)-11,11-dimethyl-10,10-diphenyl-2,4,9-trioxa-10-siladodecan-6-yl 2-((E)-2-iodovinyl)-6-methoxybenzoate 
• 1333235-58-7 (5S,6S)-6-(tert-butyldimethylsilyloxy)-10,10,11,11-tetramethyl-5-vinyl-2,4,9-trioxa-10-siladodecane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 164014-40-8 2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one 

Relevant academic research and scientific papers

Synthesis of oximidine II by a copper-mediated reductive ene-yne macrocyclization

Holy macro! An intramolecular copper-mediated reductive Castro-Stephens reaction furnished a key macrocyclic triene intermediate for the total synthesis of oximidine II (see scheme). The total synthesis of the natural product was completed and the mechanism of this unprecedented key reaction was deduced.