1333240-17-7

Basic information

• Product Name: 2-Chloro-4,5-diMethoxy-pyriMidine
• Synonyms: 2-Chloro-4,5-diMethoxy-pyriMidine
• CAS NO: 1333240-17-7
• Molecular Formula: C₆H₇ClN₂O₂
• Molecular Weight: 174.58498
• Mol File: 1333240-17-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 290.9±20.0 °C(Predicted)
• Appearance: /
• Density: 1.285±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.23±0.29(Predicted)
• CAS DataBase Reference: 2-Chloro-4,5-diMethoxy-pyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4,5-diMethoxy-pyriMidine(1333240-17-7)
• EPA Substance Registry System: 2-Chloro-4,5-diMethoxy-pyriMidine(1333240-17-7)

Safety Data

• Hazardous Substances Data: 1333240-17-7(Hazardous Substances Data)

Usage

Uses

2-Chloro-4,5-dimethoxypyrimidine is used as a reactant in the preparation of aryl-substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones as inhibitors of influenza A endonuclease.

Upstream product

• 67-56-1 methanol 
• 19646-07-2 2,4-dichloro-5-methoxypyrimidine 

Downstream Products

• 1333240-16-6 5-hydroxy-2-(4-trifluoromethyl-phenyl)-3H-pyrimidin-4-one 
• 1581767-50-1 2-(4-fluorophenyl)-4,5-dimethoxypyrimidine 
• 1581767-54-5 3-(4,5-dimethoxypyrimidin-2-yl)benzonitrile 
• 1581767-52-3 4-(4,5-dimethoxypyrimidin-2-yl)benzonitrile 
• 1581767-55-6 3-(5-methoxy-6-oxo-1,6-dihydropyrimidin-2-yl)benzonitrile 
• 1581767-53-4 4-(5-methoxy-6-oxo-1,6-dihydropyrimidin-2-yl)benzonitrile 
• 1581767-51-2 2-(4-fluorophenyl)-5-methoxypyrimidin-4(3H)-one 

Relevant articles and documents

THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES

The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS

The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved.