1333260-69-7Relevant articles and documents
Highly enantioselective [3+2] annulation of Morita-Baylis-Hillman adducts mediated by L-threonine-derived phosphines: Synthesis of 3-spirocyclopentene-2- oxindoles having two contiguous quaternary centers
Zhong, Fangrui,Han, Xiaoyu,Wang, Youqing,Lu, Yixin
, p. 7837 - 7841 (2011)
Spiral bound: The Morita-Baylis-Hillman adducts were employed as C 3 synthons in the asymmetric [3+2] annulation with malonitrile substrates using L-threonine-derived 1 as the catalyst (see scheme). The reaction is highly regioselective and ste