1333264-06-4 Usage
Uses
Used in Organic Synthesis:
[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol is used as a building block for the synthesis of complex organic molecules. Its boronic ester group allows for Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in the construction of various organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol is used as a starting material for the development of new pharmaceuticals. The presence of the fluoro group in [4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol can enhance its biological and pharmacological properties, making it a valuable component in the design and synthesis of novel drugs.
Used in Pharmaceutical Industry:
[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol is used as a key intermediate in the production of various pharmaceuticals. Its unique structure and reactivity make it a valuable asset in the development of new drugs with improved efficacy and selectivity.
Used in Research and Development:
In the research and development sector, [4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol is used as a versatile compound for exploring new chemical reactions and understanding the properties of fluorinated boronic esters. This knowledge can be applied to the development of new materials and technologies in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1333264-06-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,3,2,6 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1333264-06:
(9*1)+(8*3)+(7*3)+(6*3)+(5*2)+(4*6)+(3*4)+(2*0)+(1*6)=124
124 % 10 = 4
So 1333264-06-4 is a valid CAS Registry Number.
1333264-06-4Relevant academic research and scientific papers
HETEROCYCLIC INHIBITORS OF MONOCARBOXYLATE TRANSPORTERS
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Page/Page column 27; 28; 40, (2016/08/17)
The invention provides compounds that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.
Synthesis of boron-containing primary amines
Chung, Sheng-Hsuan,Lin, Ting-Ju,Hu, Qian-Yu,Tsai, Chia-Hua,Pan, Po-Shen
, p. 12346 - 12367 (2013/11/06)
In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters in good to excellent yields. These compounds were further utilized to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) under microwave irradiation. The prepared Ugi-4CR boronate esters were then successfully converted to the corresponding boronic acids. Finally, the peptoid structures were successfully modified by cross-coupling to aryl/heteroaryl chlorides via a palladium-mediated Suzuki coupling reaction to yield the corresponding derivatives in moderate to good yields.
