13333-49-8Relevant academic research and scientific papers
Iodine(III)-Catalyzed Electrophilic Nitration of Phenols via Non-Br?nsted Acidic NO2+ Generation
Juárez-Ornelas, Kevin A.,Jiménez-Halla, J. Oscar C.,Kato, Terumasa,Solorio-Alvarado, César R.,Maruoka, Keiji
, p. 1315 - 1319 (2019)
The first catalytic procedure for the electrophilic nitration of phenols was developed using iodosylbenzene as an organocatalyst based on iodine(III) and aluminum nitrate as a nitro group source. This atom-economic protocol occurs under mild, non-Br?nsted acidic and open-flask reaction conditions with a broad functional-group tolerance including several heterocycles. Density functional theory (DFT) calculations at the (SMD:MeCN)Mo8-HX/(LANLo8+f,6-311+G) level indicated that the reaction proceeds through a cationic pathway that efficiently generates the NO2+ ion, which is the nitrating species under neutral conditions.
HETEROCYCLIC ACIDS
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, (2008/06/13)
The invention concerns novel 1,3-dioxane alkenoic acid derivatives of the formula I wherein: n is the integer 1 or 2; Y is methyleneoxy, vinylene or ethylene; A1 is (1-6C)alkylene; R1 is a group of the formula R2A2 --, in which: R2 is phenyl unsubstituted
