1333375-54-4

Basic information

• Product Name: N-methyl-S-difluoromethyl-S-phenylsulfoximine
• Synonyms: N-methyl-S-difluoromethyl-S-phenylsulfoximine
• CAS NO: 1333375-54-4
• Molecular Weight: 205.228
• Mol File: 1333375-54-4.mol

Chemical Properties

• CAS DataBase Reference: N-methyl-S-difluoromethyl-S-phenylsulfoximine(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-S-difluoromethyl-S-phenylsulfoximine(1333375-54-4)
• EPA Substance Registry System: N-methyl-S-difluoromethyl-S-phenylsulfoximine(1333375-54-4)

Safety Data

• Hazardous Substances Data: 1333375-54-4(Hazardous Substances Data)

Upstream product

• 1333375-53-3 (difluoromethyl)(imino)(phenyl)-λ⁶-sulfanone 
• 420-37-1 trimethoxonium tetrafluoroborate 

Relevant articles and documents

N,N-Dimethyl-S-difluoromethyl-S-phenylsulfoximinium tetrafluoroborate: A versatile electrophilic difluoromethylating reagent

Over the past decade, sulfur-based fluoromethyl containing compounds have been exhaustively investigated as versatile fluoroalkylating reagents by our research laboratory as well as many others. Lately, we have designed a novel electrophilic difluoromethylating protocol employing in situ prepared N,N-dimethyl-S-difluoromethyl-S-phenylsulfoximinium salt. The present reagent provides excellent reactivity toward a broad spectrum of nucleophilic species (N-, P-, S-, and O-nucleophiles) to yield the corresponding difluoromethylated products with high efficacy under mild conditions. Additional studies have been performed to elucidate the mechanistic fundamentals of the reactions.