1333386-02-9Relevant academic research and scientific papers
Palladium-NHC catalyzed enantioselective synthesis of fused indolines via inert C(sp3)-H activation
Nakanishi, Masafumi,Katayev, Dmitry,Besnard, Celine,Kuendig, E. Peter
, p. 241 - 243 (2012)
New sterically hindered chiral N-heterocyclic carbene (NHC) ligands were used in palladium catalysis to bring about a highly enantioselective C(sp 3)-H activation on the methylene site of a cycloalkane moiety. The intramolecular coupling reacti
Fused indolines by palladium-catalyzed asymmetric C-C coupling involving an unactivated methylene group
Nakanishi, Masafumi,Katayev, Dmitry,Besnard, Celine,Kuendig, E. Peter
, p. 7438 - 7441 (2011/09/16)
Selectivity at high temperatures: Bulky, thermally stable, chiral palladium complexes generated from N-heterocyclic carbenes (NHCs; see picture) were successfully applied to the synthesis of highly enantioenriched trans-fused indolines. Remarkably, this r
