1333503-09-5Relevant academic research and scientific papers
Synthesis and Fungicidal Activities of Novel 1,2,4-Triazole Thione Derivatives Containing 1,2,3-Triazole and Substituted Piperazine Moieties
Wang, Bao-Lei,Zhan, Yi-Zhou,Zhang, Li-Yuan,Zhang, Yan,Zhang, Xiao,Li, Zheng-Ming
, p. 48 - 54 (2016)
A series of novel 1,2,4-triazole thione derivatives containing 1,2,3-triazole and substituted piperazine moieties were synthesized via the Mannich reaction of 1,2,3-triazole-containing 1,2,4-triazole thiol intermediates with various substituted piperazines and formaldehyde in high yields. The structures of 14 title compounds were confirmed by melting points, IR, 1H NMR, 13C NMR, and elemental analysis. The bioassay results showed that some of the title compounds exhibit significant fungicidal activities against several plant fungi at 50 μg/mL, especially trifluoromethyl-containing triazole thione derivative 9g showed broad activities and could be made further structural optimization for novel fungicides innovation research.
Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by Cu(II)-imine complex
Wan, Ning Ning,Yang, Yong Lei,Wang, Wen Ping,Xie, Zheng Feng,Wang, Ji De
body text, p. 1155 - 1158 (2012/01/06)
A series of new ligands L1-L7 were readily prepared in one step. Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by a novel Cu(II)-L complex has been developed. The remarkable advantages of this reaction are mild rea
