133377-94-3

Upstream product

• 133377-98-7 (2S,3R)-2-Benzyloxymethoxymethyl-pentane-1,3-diol 
• 133377-93-2 (4R,5R)-5-Benzyloxymethoxymethyl-4-ethyl-2,2-dimethyl-[1,3]dioxane 
• 133377-88-5 (2R,3R)-2-Benzyloxymethoxymethyl-1-(tert-butyl-dimethyl-silanyloxy)-pentan-3-ol 
• 197391-49-4 (2S,3R)-2-[Methylsulfanyl-(toluene-4-sulfonyl)-methyl]-pentane-1,3-diol 
• 167700-87-0 2-[Methylsulfanyl-(toluene-4-sulfonyl)-methyl]-pentane-1,3-diol 
• 197391-47-2 (4R,5S)-4-Ethyl-2,2-dimethyl-5-[methylsulfanyl-(toluene-4-sulfonyl)-methyl]-[1,3]dioxane 

Relevant academic research and scientific papers

Highly stereoselective radical addition to 3-Hydroxy-1-(methylthio)-1-(p-tolylsulfonyl)-1-alkanes and its application to the preparation of optically active compounds

Efficient 1,2-asymmetric induction was realized in the addition of a 1-hydroxyalkyl radical (R2C-OH to 3-hydroxy-1-methylthio)-1-(p-tolylsulfonyl)-1-alkenes and their acetates (1): Irradiation of 1 and benzophenone in an alcohol (R2CHOH) gave a

Enantiospecific and diastereoselective synthesis of C11-C17 fragment of tylonolide from "asymmetrized tris (hydroxymethyl)methane"

The fragment C11-C17 of tylonolide 2 was straightforwardly and stereoselectively synthesized starting from monoacetate 5, which is a synthetic equivalent of "asymmetrized tris (hydroxymethyl)methane" 3.