1333964-81-0

Basic information

• Product Name: benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate
• Synonyms: benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate
• CAS NO: 1333964-81-0
• Molecular Weight: 278.305
• Mol File: 1333964-81-0.mol

Chemical Properties

• CAS DataBase Reference: benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate(1333964-81-0)
• EPA Substance Registry System: benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate(1333964-81-0)

Safety Data

• Hazardous Substances Data: 1333964-81-0(Hazardous Substances Data)

Upstream product

• 862259-02-7 trans-(3R,4R)-3,4-bis(methoxycarbonyl)cyclopentanol 
• 100-51-6 benzyl alcohol 
• 1703-61-3 racemic trans-cyclopentanone-3,4-dicarboxylic acid 
• 115794-30-4 (+)-(1S,2S)-dimethyl-4-oxocyclopentane 1,2-dicarboxylate 
• 1703-61-3 (1R,2R)-4-oxocyclopentane-1,2-dicarboxylic acid 
• 67885-98-7 (1R,2R)-4-hydroxycyclopentane-1,2-dicarboxylic acid 
• 1027355-51-6 3-oxo-2-oxa-bicyclo[2.2.1]heptane-5-carboxylic acid 

Downstream Products

• 923604-56-2 ethyl (1R,2S)-2-ethenyl-1-({[(1R,2R,4R)-2-[hex-5-en-1-yl-(methyl)carbamoyl]-4-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)cyclopentyl]carbonyl}-amino)cyclopropanecarboxylate 
• 1042695-87-3 methyl (1R,2R,4S)-2-[5-hexen-1-yl(methyl)carbamoyl]-4-[[2-(4-isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methyl-4-quinolinyl]oxy]cyclopentanecarboxylate 
• 1333964-98-9 (1R,2R,4R)-2-(methoxycarbonyl)-4-[(4-nitrobenzoyl)oxy]cyclopentanecarboxylic acid 
• 1333965-01-7 (1R,3R,4R)-3-[5-hexen-1-yl(methyl)-carbamoyl]-4-(methoxycarbonyl)cyclopentyl 4-nitrobenzoate 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS

This disclosure provides pharmaceutical compounds to treat medical disorders, such as complement-mediated disorders, including complement Cl -mediated disorders.

PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV

A process for preparing [(1R,2R)-4-oxo-1,2-cyclopentanedicarboxylic acid II, by the resolution of racemic 4-oxo-1,2-cyclopentanedicarboxylic acid (V), said process comprising: (a) reacting 4-oxo-1,2-cyclopentanedicarboxylic acid (V) with brucine or (1R,2S)-(-)- ephedrine, thus preparing the bis-brucine or bis-(1R,2S)-(-)-ephedrine salt of (V), and (b) precipitating selectively the bis-brucine or bis-(1R,2S)-(-)-ephedrine salt of (1R,2R)-4-oxo-1,2-cyclopentanedicarboxylic acid II, while the bis-brucine or bis- (1R,2S)-(-)-ephedrine salt of [(1S,2S)-4-oxo-1,2-cyclopentanedicarboxylic acid stays in solution; (c) liberating the acid II by removal of brucine or (1R,2S)-(-)-ephedrine from the precipitated salt obtained in step (b).