1334106-85-2

Upstream product

• 1236078-07-1 2-chloro-4-phenyl-7H-pyrrolo[2,3-d]pyrimidine 
• 1334106-80-7 tert-butyl 2-chloro-4-phenyl-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 
• 1334106-82-9 tert-butyl 2-(4-ethoxyphenyl)-4-phenyl-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 
• 90213-66-4 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1334106-88-5 4-[2-(4-ethoxyphenyl)-4-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl]benzonitrile 

Relevant academic research and scientific papers

Synthesis of 4-aryl-, 2,4-diaryl- and 2,4,7-triarylpyrrolo[2,3-d] pyrimidines by a combination of the Suzuki cross-coupling and N-arylation reactions

A simple and facile synthesis of novel 4-aryl-2-chloro-, 2,4-diaryl- and 2,4,7-triarylpyrrolo[2,3-d]pyrimidines with various aryl and heteroaryl assemblies in the heterocyclic framework by a combination of Suzuki cross-coupling and N-arylation reactions of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids and haloarenes are described. A majority of the synthesized compounds were found to emit in a near UV-blue spectral range with fluorescence quantum yields up to 67%. The impact of aryl groups attached to the pyrrole ring of pyrrolopyrimidine derivatives on optical properties is discussed.

Pyrrolo[2,3-d]pyrimidine-core-extended π-systems: Synthesis of 2,4,7-triarylpyrrolo[2,3- d ]pyrimidines

A simple and facile synthesis of novel fluorescent pyrrolo[2,3-d] pyrimidines with various aryl and heteroaryl assemblies in positions 2, 4, and 7 of the heterocycle by combination of the Suzuki cross-coupling and copper(I) iodide N-arylation reactions of chloropyrrolo[2,3-d]pyrimidines with arylboronic acids and haloarenes is described. Georg Thieme Verlag Stuttgart · New York.