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Upstream product

• 1236078-12-8 2,4-diphenyl-7H-pyrrolo[2,3-d]pyrimidine 
• 36809-26-4 4-N,N-diphenylamino-1-bromobenzene 
• 90213-66-4 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 
• 98-80-6 phenylboronic acid 
• 38257-52-2 4-(N,N-diphenylamino)iodobenzene 

Relevant academic research and scientific papers

Optical study of the formation of pyrrolo[2,3-d]pyrimidine-based fluorescent nanoaggregates

Pyrrolo[2,3-d]pyrimidine derivatives possessing different sterically-hindered end-groups at position 7 of the heterocycle were studied and compared with respect to nanoaggregate formation ability by the reprecipitation method in aqueous solutions. The emergence of nanoaggregates with an increasing water fraction in THF/water mixture was traced by observing sudden changes in spectral and transient fluorescence dynamics accompanied by fluorescence efficiency turn-on. The aggregation induced emission with a maximal 20-fold emission efficiency enhancement was obtained. Tuning of the nanoaggregates sizes from about 50 nm to 600 nm by increasing the THF/water ratio was revealed by electron microscopy. Almost perfect spherical shapes of the nanoaggregates and their structureless fluorescence bands similar to those of their neat amorphous films suggested an amorphous-like nature of the pyrrolo[2,3-d]pyrimidine-based nanoparticles.

Synthesis of 4-aryl-, 2,4-diaryl- and 2,4,7-triarylpyrrolo[2,3-d] pyrimidines by a combination of the Suzuki cross-coupling and N-arylation reactions

A simple and facile synthesis of novel 4-aryl-2-chloro-, 2,4-diaryl- and 2,4,7-triarylpyrrolo[2,3-d]pyrimidines with various aryl and heteroaryl assemblies in the heterocyclic framework by a combination of Suzuki cross-coupling and N-arylation reactions of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids and haloarenes are described. A majority of the synthesized compounds were found to emit in a near UV-blue spectral range with fluorescence quantum yields up to 67%. The impact of aryl groups attached to the pyrrole ring of pyrrolopyrimidine derivatives on optical properties is discussed.

Pyrrolo[2,3-d]pyrimidine-core-extended π-systems: Synthesis of 2,4,7-triarylpyrrolo[2,3- d ]pyrimidines

A simple and facile synthesis of novel fluorescent pyrrolo[2,3-d] pyrimidines with various aryl and heteroaryl assemblies in positions 2, 4, and 7 of the heterocycle by combination of the Suzuki cross-coupling and copper(I) iodide N-arylation reactions of chloropyrrolo[2,3-d]pyrimidines with arylboronic acids and haloarenes is described. Georg Thieme Verlag Stuttgart · New York.