1334170-01-2

Basic information

• Product Name: Bis-PEG7-PFP ester
• Synonyms: Bis-PEG7-PFP ester;PFP-PEG7-PFP
• CAS NO: 1334170-01-2
• Molecular Formula: C30H32F10O11
• Molecular Weight: 758.552512
• Mol File: 1334170-01-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bis-PEG7-PFP ester(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-PEG7-PFP ester(1334170-01-2)
• EPA Substance Registry System: Bis-PEG7-PFP ester(1334170-01-2)

Safety Data

• Hazardous Substances Data: 1334170-01-2(Hazardous Substances Data)

Usage

Description

Bis-PEG7-PFP ester is a PEG (polyethylene glycol) linker containing two PFP (pentafluorophenyl) ester moieties. PFP esters are activated esters that readily react with primary amines to form stable amide bonds. The hydrophilic PEG linker enhances the water solubility of compounds in aqueous media, making Bis-PEG7-PFP ester a versatile molecule for various applications.

Uses

Used in Bioconjugation:
Bis-PEG7-PFP ester is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces. The PFP ester moieties facilitate the formation of stable amide bonds with primary amines, allowing for the efficient and specific attachment of proteins, peptides, or other amine-containing molecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bis-PEG7-PFP ester is used as a drug delivery agent to improve the solubility and stability of therapeutic agents. The PEG linker enhances the water solubility of hydrophobic drugs, while the PFP ester moieties can be used to attach drugs to targeting molecules or carriers, such as nanoparticles or liposomes, for enhanced delivery and therapeutic efficacy.
Used in Diagnostic Imaging:
In the field of diagnostic imaging, Bis-PEG7-PFP ester is used as a contrast agent for enhancing the visibility of specific tissues or structures. The PEG linker can be functionalized with imaging agents, such as fluorescent dyes or radionuclides, and the PFP ester moieties can be used to attach these agents to targeting molecules for selective imaging of diseased tissues.
Used in Tissue Engineering:
In tissue engineering, Bis-PEG7-PFP ester is used as a component of hydrogels or other scaffolds for promoting cell adhesion, growth, and tissue regeneration. The PEG linker provides a hydrophilic and biocompatible environment for cell attachment, while the PFP ester moieties can be used to attach cell adhesion peptides or other bioactive molecules to the scaffold for enhanced tissue integration and repair.