133420-98-1Relevant articles and documents
Divergent synthesis of (6S,1′S,2′R)-hydroxypestalotin via tandem conjugate addition-lactonization sequence
Mallula, Venkata Satyanarayana,Srinivas, Batthula,Radha Krishna, Palakodety
, p. 1115 - 1117 (2015/02/19)
The stereoselective synthesis of (6S,1′S,2′R)-hydroxypestalotin from trans-hex-2-en-1-ol utilizing asymmetric dihydroxylation and Luche's reduction and tandem conjugative addition-lactonization as the key steps is reported.
Chemoenzymatic total synthesis of the phytotoxic lactone herbarumin III
Nanda, Samik
, p. 3661 - 3663 (2007/10/03)
Asymmetric total synthesis of phytotoxic nonenolide herbarumin III was accomplished by a chemoenzymatic approach. The main highlight of the synthesis was to fix the hydroxyl stereocenters (C7 and C9) by lipase catalyzed irreversible transesterification.
Synthesis of O-Protected (R)-2-Hydroxy Aldehyde and Their Hydrocyanation
Effenberger, Franz,Hopf, Martin,Ziegler, Thomas,Hudelmayer, Jochen
, p. 1651 - 1659 (2007/10/02)
The synthesis of O-silyl- and O-benzyl-protected (R)-2-hydroxy aldehydes (R)-6 from (R)-2-hydroxy carboxylic acids (R)-1 is described.While attempts for their diastereoselective hydrocyanation with hydrocyanic acid and (R)-oxynitrilase as catalyst have not been successful, the cyano silylation with trimethylsilyl cyanide occurred diastereoselectively with a ratio of 81:19 preferring the threo form without racemization at C-2 of the 2-hydroxy aldehyde. Key Words : (R)-2-Hydroxy aldehydes, O-protected / Hydrocyanation