1334232-80-2Relevant academic research and scientific papers
Amine-bis(phenolate) Iron(III)-Catalyzed Formal Hydroamination of Olefins
Zhu, Kailong,Shaver, Michael P.,Thomas, Stephen P.
, p. 977 - 980 (2016)
A practical synthesis of highly functionalized amines by the formal hydroamination reaction of alkenes with nitroarenes catalyzed by an air stable amine-bis(phenolate) iron(III) complex is reported. The reaction uses an easily handled silane, low catalyst loadings, and mild reaction conditions. A wide range of substrates are transformed with synthetically useful yields (21 examples).
Titanium-mediated amination of Grignard reagents using primary and secondary amines
Barker, Timothy J.,Jarvo, Elizabeth R.
, p. 8325 - 8328 (2011/10/31)
Make it, then break it: N-chlorosuccinimide (NCS) was employed as the oxidant in the synthesis of aniline derivatives using the title transformation (see scheme). Functionalization was well tolerated on both the amine and Grignard reagent. An androgen receptor agonist and several analogues were synthesized to demonstrate the utility of this method.
