133433-38-2Relevant academic research and scientific papers
Oxidative functionalization of benzylic C-H bonds by DDQ
Batista, Victor S.,Crabtree, Robert H.,Konezny, Steven J.,Luca, Oana R.,Praetorius, Jeremy M.
, p. 1141 - 1144 (2012)
C-H activation of the methyl group of toluene and related ArCH3 derivatives by 2,3-dichloro-4,5-dicyano-1,4-benzoquinone (DDQ) gives insertion products, ArCH2O[C6Cl2(CN)2]OH via a rate-determining hydride abstraction by DDQ. The resulting benzylic ether can undergo reactions with phosphines to give benzylic phosphonium salts (Wittig reagents) and with phosphites to give phosphonate esters (Horner-Wadsworth- Emmons reagents). The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2012.
