1334331-34-8Relevant academic research and scientific papers
Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series
Achermann, Guido,Ballard, Theresa M.,Blasco, Francesca,Broutin, Pierre-Emmanuel,Buettelmann, Bernd,Fischer, Holger,Graf, Martin,Hernandez, Maria-Clemencia,Hilty, Peter,Knoflach, Frederic,Koblet, Andreas,Knust, Henner,Kurt, Anke,Martin, James R.,Masciadri, Raffaello,Porter, Richard H.P.,Stadler, Heinz,Thomas, Andrew W.,Trube, Gerhard,Wichmann, Juergen
, p. 5746 - 5752 (2009)
Through iterative design cycles we have discovered a number of novel new classes where the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine was deemed the most promising GABAA α5 inverse agonist class with potential for cognitive enhanc
