1334336-59-2Relevant academic research and scientific papers
Rhodium-catalyzed decarbonylative direct olefination of arenes with vinyl carboxylic acids
Qiu, Ruiying,Zhang, Lingjuan,Xu, Conghui,Pan, Yixiao,Pang, Hongze,Xu, Lijin,Li, Huanrong
supporting information, p. 1229 - 1236 (2015/04/22)
A rhodium(I)-catalyzed direct C-H bond olefination of pyridyl-substituted arenes with readily available vinyl carboxylic acids has been realized. This reaction occurred efficiently without the need for any external oxidant, affording the ortho-olefinated products in high yields and excellent regioselectivities. Diversely substituted vinyl carboxylic acids behaved as efficient olefination reagents under the reaction conditions, and a range of functional groups in both coupling partners was well tolerated. Mechanistic studies indicated that a decarbonylation step is involved in this catalytic process, and pivalic anhydride [(t-BuCO)2O] acts as the activator of the carboxylic acids for the in situ generation of highly active anhydrides.
Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols
Li, Hu,Li, Yang,Zhang, Xi-Sha,Chen, Kang,Wang, Xin,Shi, Zhang-Jie
supporting information; experimental part, p. 15244 - 15247 (2011/11/05)
Novel C-C bond cleavage of secondary alcohols through Rh(III)-catalyzed β-carbon elimination directed by a pyridinyl group is reported. A five-membered rhodacycle is proposed as a key intermediate, which undergoes further alkenylation with various olefins. This novel transformation shows high efficiency along with excellent selectivity in mild conditions. A wide range of functionalities are compatible. This study offers a new strategy to carry out C-C bond activation.
