1334368-34-1

Basic information

• Product Name: 2-[2-(2-bromophenyl)-3-oxoindolin-2-yl]acetaldehyde
• CAS NO: 1334368-34-1
• Molecular Weight: 330.181
• Mol File: 1334368-34-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[2-(2-bromophenyl)-3-oxoindolin-2-yl]acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(2-bromophenyl)-3-oxoindolin-2-yl]acetaldehyde(1334368-34-1)
• EPA Substance Registry System: 2-[2-(2-bromophenyl)-3-oxoindolin-2-yl]acetaldehyde(1334368-34-1)

Safety Data

• Hazardous Substances Data: 1334368-34-1(Hazardous Substances Data)

Upstream product

• 75-07-0 acetaldehyde 
• 325765-87-5 2-(2-bromophenyl)-3H-indol-3-one 

Relevant articles and documents

Asymmetric proline-catalyzed addition of aldehydes to 3H-indol-3-ones: Enantioselective synthesis of 2,3-dihydro-1H-indol-3-ones with quaternary stereogenic centers

The proline-catalyzed addition of various aliphatic aldehydes to sterically hindered 2-aryl-substituted 3H-indol-3-ones affords 2,2-disubstituted 2,3-dihydro-1H-indol-3-one derivatives with excellent enantioselectivities. In addition, the synthesis of a chiral derivative, (S)-2-(2-bromophenyl)-2,3- dihydro-2-(2-hydroxyethyl)-1H-indol-3-one, which can be used as an intermediate for the preparation of the natural product hinckdentine A was accomplished with a high level of enantioselectivity.