1334429-75-2Relevant academic research and scientific papers
Umpolung reactivity of indole through gold catalysis
Lu, Biao,Luo, Yingdong,Liu, Lianzhu,Ye, Longwu,Wang, Yanzhao,Zhang, Liming
supporting information; experimental part, p. 8358 - 8362 (2011/10/31)
Electrophilic indole? Indoles, which are typically nucleophilic, can be made electrophilic through gold catalysis. By using an ortho-azido group to deliver a nitrene intramolecularly, an arylalkyne is converted into a gold carbene intermediate containing an indole skeleton that is highly electrophilic at the 3-position. A range of functionalized indoles is readily accessed by utilizing this strategy.
