133444-84-5

Basic information

• Product Name: S-2-Aminononanoic acid
• Synonyms: S-2-Aminononanoic acid;S-2-AMinononanoic acid S-2-AMinononanoic acid
• CAS NO: 133444-84-5
• Molecular Formula: C9H19NO2
• Molecular Weight: 173.25266
• Mol File: 133444-84-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 284.5±23.0 °C(Predicted)
• Appearance: /
• Density: 0.985±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.55±0.24(Predicted)
• CAS DataBase Reference: S-2-Aminononanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: S-2-Aminononanoic acid(133444-84-5)
• EPA Substance Registry System: S-2-Aminononanoic acid(133444-84-5)

Safety Data

• Hazardous Substances Data: 133444-84-5(Hazardous Substances Data)

Usage

General Description

S-2-Aminononanoic acid, also known as S-2-aminononanoate or S-2-Aminononanoic acid, is an organic compound that consists of a nine-carbon chain with an amino group attached at the 2-position. It is classified as an alpha-amino acid and is a non-proteinogenic amino acid, meaning it is not used by the body to build proteins. S-2-Aminononanoic acid is used in the synthesis of various pharmaceuticals and as a chiral building block in organic chemistry. It has also been studied for its potential as a corrosion inhibitor and as a surfactant in industrial applications. Overall, S-2-Aminononanoic acid has a variety of uses across different fields due to its unique chemical properties.

Upstream product

• 70215-04-2 2-hydroxynonanoic acid 
• 112-05-0 nonanoic acid 
• 56275-57-1 ethyl 2-oxononaoate 
• 629-04-9 1-Bromoheptane 
• 13139-94-1 2-oxononanoic acid 

Downstream Products

• 1339952-66-7 (S)-2-(3-((S)-1-carboxyoctyl)ureido)-6-(4-iodobenzamido)hexanoic acid 

Relevant articles and documents

A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde

2-Dibenzylamino-5-oxopentanoic acid benzyl ester has been obtained in good yields by complete benzylation of L-glutamic acid in NaOH and Na 2CO3, selective reduction of the γ-ester into alcohol with DIBAL and further transformation into aldehyde using Swern oxidation. The overall three-step procedure from Glu gave aldehyde in 49% yield. Georg Thieme Verlag Stuttgart.

Preparative Asymmetric Synthesis of Canonical and Non-canonical a-amino Acids through Formal Enantioselective Biocatalytic Amination of Carboxylic Acids

Chemical and biocatalytic synthesis of non-canonical a-amino acids (ncAAs) from renewable feedstocks and using mild reaction conditions has not efficiently been solved. Here, we show the development of a three-step, scalable and modular one-pot biocascade for linear conversion of renewable fatty acids (FAs) into enantiopure l-a-amino acids. In module 1, selective a-hydroxylation of FAs is catalyzed by the P450 peroxygenase P450CLA. By using an automated H2O2 supplementation system, efficient conversion (46 to >99%; TTN>3300) of a broad range of FAs (C6:0 to C16:0) into valuable a-hydroxy acids (a-HAs; >90% a-selective) is shown on preparative scale (up to 2.3 gL1 isolated product). In module 2, a redox-neutral hydrogen borrowing cascade (alcohol dehydrogenase/amino acid dehydrogenase) allowed further conversion of a-HAs into l-a-AAs (20 to 99%). Enantiopure l-a-AAs (e.e. >99%) including the pharma synthon l-homo-phenylalanine can be obtained at product titers of up to 2.5 gL1. Based on renewables and excellent atom economy, this biocascade is among the shortest and greenest synthetic routes to structurally diverse and industrially relevant ncAAs.

Enantioselective synthesis of (S)-amino acids by phenylalanine dehydrogenase from Bacillus sphaericus: use of natural and recombinant enzymes

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