13345-51-2 Usage
Uses
Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.
Enzyme inhibitor
This eicosanoid (FWB1 (free-acid) = 336.47 g/mol; CAS 13345-51-2, for PGB1,
and 39306-29-1, for Bx) is a metabolite of prostaglandin E1: prostaglandin
Bx is an oligomer of prostaglandin B1. The X-ray crystal structure of
prostaglandin B1 suggests this prostaglandin has an unusual L-shaped
configuration, with the a and w side chains roughly perpendicular to one
another. The 15-hydroxyl group, which is normally directed away from
the centroid of the prostaglandin in the standard hairpin mod+el, is turned
inward in prostaglandin B1. Target (s) : FoF1 ATPase, or H-transporting
two-sector ATPase, inhibited by prostaglandin Bx; 15-
hydroxyprostaglandin dehydrogenase; phospholipase A2, inhibited by
prostaglandin Bx.
Check Digit Verification of cas no
The CAS Registry Mumber 13345-51-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,4 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13345-51:
(7*1)+(6*3)+(5*3)+(4*4)+(3*5)+(2*5)+(1*1)=82
82 % 10 = 2
So 13345-51-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,17,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t17-/m0/s1
