1334524-01-4Relevant articles and documents
Design, synthesis, biological evaluation, and molecular docking of novel flavones as H3R inhibitors
Wen, Gang,Liu, Qian,Hu, Huabin,Wang, Dongmei,Wu, Song
, p. 580 - 589 (2017/09/14)
A series of novel flavone derivatives were designed, synthesized, and evaluated for their H3R inhibitory activity. The results showed that four compounds exhibited significant anti-H3R activity. Molecular docking experiments indicated that a salt bridge, hydrogen-bonding, and hydrophobic interactions all contributed to interactions between inhibitors and H3R.