1334544-50-1Relevant articles and documents
Synthesis of glibenclamide-pregnenolone conjugate and its relationship with physico-chemical descriptors log P, π, Rm, Vm, P c and St
Figueroa-Valverde, Lauro,Díaz-Cedillo, Francisco,López-Ramos, Maria,Garcia-Cervera, Elodia,Ancona-Leon, Josefina,Pool-Gómez, Jose E.
experimental part, p. 3999 - 4002 (2012/01/12)
In this study, a glibenclamide-pregnenolone conjugate was synthesized. The route involved a reaction of substitution of chloride atom involved in the chemical structure of glibenclamide to form the compound 2 using sodium hydroxide. Additionally, the comp