1334544-60-3Relevant academic research and scientific papers
A facile one-pot synthesis of 1,3,4-thiadiazine-5-yl-pyran-2-one derivatives via a multicomponent reaction
Penta, Santhosh,Vedula, Rajeswar Rao
experimental part, p. 327 - 333 (2011/12/02)
A facile synthesis of 1,3,4-thiadiazine-5-yl-pyran-2-one derivatives is achieved via a three-component reaction involving 3-(2-bromoacetyl)-4-hydroxy-6- methyl-2H-pyran-2-one, thiocarbohydrazide with various carbonyl compounds in one-pot under stirring. The main advantage of this procedure is the short reaction time, high yields, simple workup, and purification of products by non-chromatographic methods, i.e. by simple recrystallization from ethanol. The structures of newly prepared compounds have been established by elemental analysis and spectral data.
