1334548-48-9Relevant academic research and scientific papers
Synthesis and antimicrobial evaluation of some new thienopyridine, pyrazolopyridine and pyridothienopyrimidine derivatives
Rateb, Nora M.,Abdelaziz, Shaimaa H.,Zohdi, Hussein F.
experimental part, p. 345 - 354 (2011/12/15)
Thieno[2,3-b]pyridines 7, 8, 9 were obtained via the S-alkylation of 3 with a variety of alkylating agents followed by cyclization in a basic medium. On the other hand, compound 3 reacted with methyl iodide to give compound 10 which was converted to pyrazolo[3,4-b]pyridine derivative 13 by reaction with hydrazine hydrate. Pyrido[3′, 2′:4,5]thieno[3,2-d]pyrimidines derivatives 14, 16 were obtained by reaction of 7 with each of formic acid and formic/formamide, respectively. Furthermore, compound 14 was obtained by the reaction of 8 with formamide. Structures of the newly synthesized products were determined by elemental analysis and spectral data.
