1334599-56-2

Basic information

• Product Name: C₂₀H₂₆N₄O₂
• CAS NO: 1334599-56-2
• Molecular Weight: 354.452
• Mol File: 1334599-56-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₆N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₆N₄O₂(1334599-56-2)
• EPA Substance Registry System: C₂₀H₂₆N₄O₂(1334599-56-2)

Safety Data

• Hazardous Substances Data: 1334599-56-2(Hazardous Substances Data)

Upstream product

• 2293-07-4 1-(4-methoxyphenyl)thiourea 
• 39536-25-9 C₁₅H₁₆N₂OS 
• 1370288-94-0 C₁₇H₁₇ClN₂O₂S 
• 1370289-35-2 C₂₁H₂₇N₃O₂S 
• 62-53-3 aniline 

Relevant articles and documents

Synthesis and antiinflammatory properties of N-substituted guanidines

Various N[(p-substituted/unsubstituted)phenyl), (substituted thiazol-2-yl/oxazol-2-yl/naphthothiazol-2-yl)],N'-[N''',N'''-dimethyl/ diethylaminoacetyl],N''-phenyl guanidines were prepared from corresponding N-substituted thiocarbamides and were evaluated for their antiinflammatory activity. All the substituted guanidines (100 mg/Kg) provided 1-79 % protection against carrageenin induced edema in rats. Phenyl butazone (100 mg/Kg) was used as a standard drug for comparative evaluation and showed greater antiinflammatory activity. The results suggest that the presence of methoxy group on phenyl nuclei at para position enhances antiinflammatory activity. The increase in chain length on alkyl group of N (R)2 skeleton also cause some enhancement in activity. Among heterocyclic molecules maximum level of antiinflammatory activity is shown by oxazol-2-yl substituted guanidines.