1334607-79-2

Upstream product

• 2357-47-3 4-Fluoro-3-trifluoromethylaniline 
• 393-37-3 5-bromo-2-fluorobenzotrifluoride 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 5419-55-6 Triisopropyl borate 
• 914635-61-3 4-bromo-1-[(1-methylethyl)oxy]-2-(trifluoromethyl)benzene 

Downstream Products

• 1344997-66-5 2-[4-[(1-methylethyl)oxy]-3-(trifluoromethyl)phenyl]-1,3-thiazole 
• 1344995-99-8 1-(2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)benzyl)piperidine-4-carboxylic acid 
• 1373522-36-1 2-((2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)phenethyl)(methyl)amino)acetic acid 
• 1373522-35-0 2-((2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)phenethyl)amino)acetic acid 
• 1373522-34-9 2-((2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)benzyl)(methyl)amino)-2-methylpropanoic acid 
• 1373522-33-8 2-((2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)benzyl)(methyl)amino)acetic acid 
• 1373522-22-5 4-(2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)phenyl)butanoic acid 
• 1373522-40-7 3-(2-ethyl-3-(2-methoxyvinyl)phenyl)-5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazole 
• 1373522-79-2 3-(5-bromo-4-ethylpyridin-3-yl)-5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazole 
• 1344997-57-4 2-(2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)phenyl)acetaldehyde 
• 1344997-56-3 3-{2-ethyl-3-[(E)-2-(methyloxy)ethenyl]phenyl}-5-[4-[(1-methylethyl)oxy]-3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole 
• 1344997-55-2 3-(3-(bromomethyl)-2-ethylphenyl)-5-(4-isopropoxy-3-(trifluoromethyl)-phenyl)-1,2,4-thiadiazole 
• 1344997-54-1 2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)benzaldehyde 
• 1344998-58-8 C₂₉H₃₄F₃N₃O₃S 

Relevant academic research and scientific papers

PYRIMIDINE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

Disclosed are pyrimidine derivatives for use as a sphingosine 1-phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions or diseases mediated by S1P1 receptors, particularly multiple sclerosis.

PYRIMIDINE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

Disclosed are pyrimidine derivatives for use as sphingosine 1- phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions or diseases mediated by S1P1 receptors, particularly multiple sclerosis.

COMPOUNDS AS AGONISTS OF S1P1 RECEPTORS

Compounds of formula (I), processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by S1P1 receptors.