1334671-47-4Relevant academic research and scientific papers
Diastereoselective and enantioselective capture of chiral zinc enolate using nitroolefins: A rapid access to chiral γ-nitro carbonyl compounds
Ni, Cheng-Yan,Kan, Sha-Sha,Liu, Quan-Zhong,Kang, Tai-Ran
, p. 6211 - 6214 (2011)
Highly diastereoselective and enantioselective catalytic capture of chiral zinc enolates using nitroolefins as electrophiles is described. The tandem products γ-nitro ketones were obtained in good yields with high diastereoselectivities and enantioselectivities. The γ-nitro ketones were readily hydrogenated to the optically enriched and diastereomerically pure chiral pyrrolidines with four contiguous stereocentres under mild conditions.
