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1334674-88-2

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1334674-88-2 Usage

General Description

(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)methanol is a chemical compound that belongs to the class of pyrrolopyrazine derivatives. It is a brominated derivative of 5H-pyrrolo[2,3-b]pyrazine with a methanol group attached to the 7-position. (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)methanol can be used as a building block in the synthesis of various biologically active molecules, such as pharmaceutical drugs and agrochemicals. It may also have potential biological activities and can be used as a research tool in the field of medicinal chemistry and chemical biology. However, further studies are needed to fully understand its properties and potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1334674-88-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,4,6,7 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1334674-88:
(9*1)+(8*3)+(7*3)+(6*4)+(5*6)+(4*7)+(3*4)+(2*8)+(1*8)=172
172 % 10 = 2
So 1334674-88-2 is a valid CAS Registry Number.

1334674-88-2Downstream Products

1334674-88-2Relevant articles and documents

DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES

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Paragraph 0358, (2015/11/27)

The present invention relates to certain diaryl macrocyclic compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating cancer, pain, neurological diseases, autoimmune diseases, and inflammation.

Its use as an inhibitor and JAK and SYK deriv. pyrroropyrazine

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Paragraph 0127; 0130, (2016/11/07)

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q, R2, R3, and Y are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.

3-amido pyrrolopyrazine JAK kinase inhibitors: Development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models

Soth, Michael,Hermann, Johannes C.,Yee, Calvin,Alam, Muzaffar,Barnett, Jim W.,Berry, Pamela,Browner, Michelle F.,Frank, Karl,Frauchiger, Sandra,Harris, Seth,He, Yang,Hekmat-Nejad, Mohammad,Hendricks, Than,Henningsen, Robert,Hilgenkamp, Ramona,Ho, Hoangdung,Hoffman, Ann,Hsu, Pei-Yuan,Hu, Dong-Qing,Itano, Andrea,Jaime-Figueroa, Saul,Jahangir, Alam,Jin, Sue,Kuglstatter, Andreas,Kutach, Alan K.,Liao, Cheng,Lynch, Stephen,Menke, John,Niu, Linghao,Patel, Vaishali,Railkar, Aruna,Roy, Douglas,Shao, Ada,Shaw, David,Steiner, Sandra,Sun, Yongliang,Tan, Seng-Lai,Wang, Sandra,Vu, Minh Diem

, p. 345 - 356 (2013/02/23)

The Janus kinases (JAKs) are involved in multiple signaling networks relevant to inflammatory diseases, and inhibition of one or more members of this class may modulate disease activity or progression. We optimized a new inhibitor scaffold, 3-amido-5-cycl

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