1334674-89-3

Upstream product

• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 1184926-29-1 2-bromo-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine 
• 3724-43-4 Vilsmeier reagent 
• 875781-43-4 2-bromo-5H-pyrrolo[2,3-b]pyrazine 

Relevant academic research and scientific papers

PYRROLO[2,3-B]PYRAZINES AS SYK INHIBITORS

The present invention relates to the use of novel pyrrolo[2,3- b]]pyrazines wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.

PYRROLOPYRAZINE KINASE INHIBITORS

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.

Pyrrolopyrazine Kinase Inhibitors

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables n, p, q, Q, X, X′ and Y are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.