13347-83-6

Upstream product

• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 100-51-6 benzyl alcohol 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 101223-84-1 1-O-benzyl-N-acetyl-4,6-O-benzylidene-D-glucosamine 
• 3055-51-4 benzyl 2-deoxy-2-(N-acetylamino)-D-glucopyranoside 
• 13343-63-0 benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside 

Downstream Products

• 13343-63-0 benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside 
• 81429-62-1 Benzyl-4,6-O-benzyliden-2-desoxy-2-(2',4'-dinitroanilino)-α-D-glucopyranosid 
• 66111-59-9 benzyl 4,6-O-benzylidene-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside 
• 4710-91-2 benzyl 2-benzamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside 
• 76379-13-0 (R)-4-((S)-3-Benzyloxy-2-{(R)-2-[(4aR,6S,7R,8R,8aS)-6-benzyloxy-7-(2-benzyloxy-acetylamino)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester 
• 76379-15-2 (R)-4-((S)-2-{(R)-2-[(4aR,6S,7R,8R,8aS)-6-Benzyloxy-7-(2-benzyloxy-acetylamino)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionylamino}-4-methyl-pentanoylamino)-4-carbamoyl-butyric acid benzyl ester 
• 76379-14-1 (R)-4-((S)-2-{(R)-2-[(4aR,6S,7R,8R,8aS)-6-Benzyloxy-7-(2-benzyloxy-acetylamino)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionylamino}-3-methyl-butyrylamino)-4-carbamoyl-butyric acid benzyl ester 
• 66112-14-9 (R)-4-((S)-2-{(R)-2-[(4aR,6S,7R,8R,8aS)-6-Benzyloxy-7-(2-benzyloxy-acetylamino)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester 
• 76379-10-7 (R)-2-[(4aR,6S,7R,8R,8aS)-6-Benzyloxy-7-(2-benzyloxy-acetylamino)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionic acid 3,5-dioxo-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl ester 
• 66111-70-4 benzyl 4,6-O-benzylidene-2-benzyloxyacetamido-3-O-<1-(R)-carboxyethyl>-2-deoxy-α-D-glucopyranoside 
• 177361-86-3 N-[(2S,3R,4R,5S,6R)-4-Azido-2-benzyloxy-6-benzyloxymethyl-5-(4-methoxy-benzyloxy)-tetrahydro-pyran-3-yl]-2,2,2-trifluoro-acetamide 
• 177361-89-6 N-((4aR,6S,7R,8R,8aS)-8-Azido-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-2,2,2-trifluoro-acetamide 

Relevant academic research and scientific papers

Sugar derived alkamine catalytic imine reduction method

The invention discloses a method used for catalytic reduction of imine with saccharide-derivatized amino alcohol. According to the method, imine is taken as a substrate. The method comprises following steps: 1) imine and saccharide-derivatized amino alcohol are dissolved in an organic solvent I, wherein molar ratio of imine to saccharide-derivatized amino alcohol ranges from 100:1-20; 2) trichlorosilane with 1.5 to 5 times equivalent weights is added into a solution obtained via step 1) dropwise, an obtained mixture is stirred and reacted for 12 to 36h at a temperature of -20 to 40 DEG C, and a saturated sodium bicarbonate solution is used for quenching; 3) a material obtained via step 2) is extracted with an organic solvent II, and is subjected to column chromatography isolation so as to obtain amine compounds.

Synthesis of novel carbohydrate-based chiral P, N ligands and their applications in Cu-catalyzed enantioselective 1, 4-conjugate additions

A new type of phosphate-pyridine (P, N) ligand derived from d-glucosamine and BINOL was synthesized and successfully applied in Cu-catalyzed enantioselective conjugate addition of diethylzinc to chalcones for the first time, high yields and enantioselectivities were obtained when the ligand 10a which contains (S)-BINOL was used. The results also showed that the configuration of BINOL at the ligand backbone had remarkable effects on the activities and enantioselectivities.

Synthesis of novel carbohydrate-based iminophosphinite ligands in Pd-catalyzed asymmetric allylic alkylations

A series of novel carbohydrate-based iminophosphinite ligands have been synthesized for the first time and successfully applied in Pd-catalyzed asymmetric allylic alkylation. The substituent effects on the catalytic reaction were also investigated, and 92% ee was achieved when the p-nitro-substituted ligand 10d was used.

A facile synthesis of benzyl 2-amino-3-azido-4-O-p-methoxybenzyl-6-O-benzyl-2,3-dideoxy-α-D- glucopyranoside: A key intermediate in the formation of a didemnin B analog

Although the deprotection of amides by hydrazinolysis is a well established method in carbohydrate chemistry, this reaction is dependent upon the nearby substituents. In our facile synthesis of intermediate benzyl 2-amino-3-azido-4-O-p-methoxybenzyl-6-O-b