1334722-64-3

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 105644-28-8 1,1-dimethoxy-1,2,3,4-tetrahydronaphthalene 
• 52340-78-0 (R,R)-hydroxybenzoin 
• 1334722-62-1 (4R,5R)-4,5-diphenyl-3',4'-dihydro-2'H-spiro[[1,3]dioxolane-2,1'-naphthalene] 

Relevant academic research and scientific papers

Asymmetric addition of dimethylzinc to alkylidenmalonates mediated by phosphorous ligands: A new synthetic route to floral fragrances

Six new phosphite ligands were prepared and their efficiency as chiral ligands was investigated in the copper-catalyzed asymmetric conjugate addition of dimethylzinc to diethyl 3-phenylpropylidenmalonate (5), affording the addition product with ees up to 74%. Moreover, a simple and straightforward route to floral fragrances Phenoxanol, Citralis, and Nitrile Citralis in optically active form through the above cited reaction was proposed. Chirality, 2011. 2011 Wiley-Liss, Inc. Copyright