1334785-34-0Relevant articles and documents
Synthesis and Na+/H+ exchanger inhibitory activity of benzoylguanidine derivatives
Jin, Lu,Jiang, Xiang-Min,Du, Ping,Xu, Jing,Gong, Guo-Qing,Wang, Qiu-Juan,Xu, Yun-Gen
, p. 4107 - 4116 (2011/11/29)
Twenty-two compounds of substituted benzoylguanidine derivatives were designed and synthesized as potent NHE1 inhibitors. Twelve compounds showed more potent NHE1 inhibitory activity than cariporide. The activities of compounds 7e, 7h and 7j (IC50/s