133480-24-7Relevant academic research and scientific papers
Trifluoromethylthiolation and trifluoromethanesulfonylation of β,γ-unsaturated hydrazones
Xiao, Hongqing,Meng, Weidong,Xu, Xiu-Hua,Huang, Yangen
, (2020)
The trifluoromethylthiolation and trifluoromethanesulfonylation of β,γ-unsaturated hydrazones was accomplished with silver(I) trifluoromethanethiolate (AgSCF3) as a CF3S source and sodium trifluoromethylsulfinate (CF3SO2Na) as a CF3SO2 source, respectively. These general methods for the preparation of dihydropyrazoles containing CF3S or CF3SO2 groups were characterized by mild reaction conditions and good functional group tolerance.
Copper-Catalyzed Diamination of Alkenes of Unsaturated Ketohydrazones with Amines
Chen, Manman,Wang, Li-Jing,Ren, Pei-Xing,Hou, Xiao-Ying,Fang, Zhang,Han, Meng-Nan,Li, Wei
supporting information, p. 510 - 513 (2018/02/10)
A convenient copper-catalyzed intra-/intermolecular diamination of β,γ-unsaturated hydrazones has been developed with simple amines as external amine sources. The protocol enables efficient access to various nitrogen-containing pyrazolines under mild reaction conditions.
In situ formation of allyl ketones via Hiyama-Nozaki reactions followed by a chromium-mediated Oppenauer oxidation
Schrekker, Henri S.,De Bolster, Martin W. G.,Orru, Romano V. A.,Wessjohann, Ludger A.
, p. 1975 - 1981 (2007/10/03)
In Hiyama-Nozaki reactions of allylchromium with aldehydes the expected products are homo-allylalcohols. However, oxidation products derived from these, predominantly allyl ketones, can be common side products. This can be explained by an Oppenauer-(Meerwein-Ponndorf-Verley)-type mechanism (OMPV-reaction). The amount of oxidation is strongly dependent on the substitution pattern of the reaction partners and the reaction conditions. An appropriate choice of these can lead to preferential formation of ketones instead of the alcohols. In addition to its synthetic usefulness, the oxidation-reduction equilibrium is of the utmost importance for the design of enantioselective Hiyama-Nozaki reactions because it is also a potential racemization pathway.
