1334880-58-8

Basic information

• Product Name: ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-fluorocyclohexanecarboxylate
• Synonyms: ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-fluorocyclohexanecarboxylate
• CAS NO: 1334880-58-8
• Molecular Weight: 289.347
• Mol File: 1334880-58-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-fluorocyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-fluorocyclohexanecarboxylate(1334880-58-8)
• EPA Substance Registry System: ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-fluorocyclohexanecarboxylate(1334880-58-8)

Safety Data

• Hazardous Substances Data: 1334880-58-8(Hazardous Substances Data)

Upstream product

• 193673-65-3 (1R,2S)-cis-2-aminocyclohex-3-enecarboxylic acid 
• 1337970-89-4 ethyl (1R,2R,3S)-2-(tert-butoxycarbonylamino)-3-hydroxycyclohex-4-enecarboxylate 
• 20205-48-5 8-oxo-7-azabicyclo<4.2.0>oct-2-ene 
• 189125-29-9 (1R,2S)-cis-2-aminocyclohex-4-enecarboxylic acid 
• 1334880-56-6 ethyl (1R,2S,5R)-2-(tert-Butoxycarbonylamino)-5-hydroxycyclohexanecarboxylate 
• 1334880-42-0 tert-butyl (1R,2S,5S)-7-oxo-6-oxabicyclo[3.2.1]oct-3-en-2-ylcarbamate 
• 1334880-41-9 tert-butyl (1R,2S,4S,5S)-4-iodo-7-oxo-6-oxabicyclo[3.2.1]octan-2-ylcarbamate 
• 1226812-49-2 (1R,6S)-6-(tert-butoxycarbonylamino)cyclohex-3-enecarboxylic acid 
• 1228186-98-8 ethyl (1R,2S,5S)-2-(tert-butoxycarbonylamino)-5-hydroxycyclohex-3-enecarboxylate 
• 870288-16-7 (1R,2S)-2-(tert-butoxycarbonylamino)cyclohex-3-enecarboxylic acid 

Relevant articles and documents

Regio- and diastereoselective fluorination of alicyclic β-amino acids

A regio- and stereoselective approach to fluorinated β- aminocyclohexene or cyclohexane esters has been developed, starting from a bicyclic β-lactam (1). The procedure involves six or seven steps, based on regio- and stereoselective iodolactonization, lactone opening and hydroxy-fluorine exchange. The method has been extended to the synthesis of fluorinated amino ester enantiomers.