1334953-25-1Relevant articles and documents
Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors
Sun, Liang-Peng,Shen, Qiang,Piao, Hong-Hua,Ma, Wei-Ping,Gao, Li-Xin,Zhang, Wei,Nan, Fa-Jun,Li, Jia,Piao, Hu-Ri
, p. 3630 - 3638 (2011/11/06)
A series of novel nonphosphonate-based pTyr mimetics comprised (±)-3-(2-(2-fluorobenzyloxy)naphthalen-6-yl)-2-aminopropanoic acid derivatives were identified as reversible and competitive PTP1B inhibitors via a structure-based design approach. Among the c