13350-09-9

Basic information

• Product Name: 1-NITRO-2-PROP-2-YNYLOXY-BENZENE
• Synonyms: 1-NITRO-2-PROP-2-YNYLOXY-BENZENE;1-NITRO-2-(PROP-2-YN-1-YLOXY)BENZENE(WXC08363)
• CAS NO: 13350-09-9
• Molecular Formula: C₉H₇NO₃
• Molecular Weight: 177.15678
• Mol File: 13350-09-9.mol
• Article Data: 31

Chemical Properties

• Melting Point: 74-76 °C
• Boiling Point: 308.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.247±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-NITRO-2-PROP-2-YNYLOXY-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-NITRO-2-PROP-2-YNYLOXY-BENZENE(13350-09-9)
• EPA Substance Registry System: 1-NITRO-2-PROP-2-YNYLOXY-BENZENE(13350-09-9)

Safety Data

• Hazardous Substances Data: 13350-09-9(Hazardous Substances Data)

Usage

Nitro-substituted propargyloxybenzene

A type of chemical compound in which a nitro group (-NO2) is attached to a propargyloxybenzene (a benzene ring with a propargyl ether functional group).

Nitro group

A functional group consisting of an oxygen atom and a nitrogen atom (-NO2), which is known to impart explosive properties and can participate in various chemical reactions.

Propargyl ether functional group

A functional group with a triple-bonded carbon atom connected to an oxygen atom and an alkyl group (in this case, a propargyl group), which can undergo addition reactions and other chemical transformations.

Building block in organic synthesis

1-nitro-2-prop-2-ynyloxy-benzene is commonly used as an intermediate compound in the synthesis of more complex organic molecules, providing a versatile starting point for various chemical reactions.

Unique structure

The presence of both a nitro group and a propargyl ether functional group attached to a benzene ring gives 1-nitro-2-prop-2-ynyloxy-benzene a distinctive structure that allows for diverse chemical reactions and applications.

Precursor in the preparation of various organic compounds

1-nitro-2-prop-2-ynyloxy-benzene serves as a starting material for the synthesis of a wide range of organic compounds, making it an important reagent in organic chemistry.

Versatility and utility

The compound's unique structure and reactivity make it valuable in the field of organic chemistry, as it can be used to create a variety of other compounds with different properties and applications.

Upstream product

• 107-19-7 propargyl alcohol 
• 1493-27-2 ortho-nitrofluorobenzene 
• 104493-07-4 3-(triisopropylsilyl)propargyl alcohol 
• 106-96-7 propargyl bromide 
• 88-75-5 2-hydroxynitrobenzene 
• 13610-02-1 1-phenoxy-2-propyne 
• 6165-75-9 propargyl benzenesulfonate 

Downstream Products

• 52536-39-7 2-(prop-2-ynyloxy)benzenediazonium tetrafluoroborate 
• 1485820-31-2 C₁₄H₁₃N₇O₅ 
• 1485821-41-7 C₁₅H₁₅N₇O₅ 
• 1485822-51-2 C₁₆H₁₇N₇O₅ 
• 1610804-90-4 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-3,5-dimethoxybenzamide 
• 1610804-91-5 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-3-methylbenzamide 
• 1610804-92-6 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-4-methylbenzamide 
• 1610804-93-7 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-4-(dimethylamino)benzamide 
• 1610804-94-8 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-nitrobenzamide 
• 1610804-95-9 N-(4-(tert-butyl)phenyl)-2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)benzamide 
• 1610804-96-0 3-chloro-N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)benzamide 
• 1610804-97-1 4-chloro-N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)benzamide 
• 1610804-98-2 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-4-fluorobenzamide 
• 1610804-99-3 N-(2-((1-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-3, 4,5-trimethoxybenzamide 

Relevant articles and documents

Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach

A series of steroidal hybrids with different terminal bioactive scaffolds were synthesized using the molecular hybridization approach and further evaluated for their antiproliferative activity against several cancer cell lines of different origins using t

A click chemistry strategy to synthesize geraniol-coupled 1,4-disubstituted 1,2,3-triazoles and exploration of their microbicidal and antioxidant potential with molecular docking profile

The present paper elicits an unprecedented synthesis of a novel series of 1,2,3-triazole compounds using geraniol as the precursor via 1,3-dipolar cycloaddition using click chemistry strategy. All the synthesized compounds were screened to evaluate their

Synthesis of sorafenib analogues incorporating a 1,2,3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines

A series of 1,2,3-triazole-containing Sorafenib analogues, in which the aryl urea moiety of Sorafenib (1) was replaced with a 1,2,3-triazole ring linking a substituted phenoxy fragment, were prepared successfully via Huisgen 1,3-dipolar cycloaddition and

Ruthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N-H Insertion: Synthesis of Benzofused Six-Membered Azaheterocycles

The Cp*RuCl-based catalyst enables expedient access to a variety of benzofused six-membered azaheterocycles from unprotected o-alkynylanilines and trimethylsilyldiazomethane through an unprecedent tandem carbene/alkyne metathesis/N-H insertion reaction. The transformation takes place under mild reaction conditions (room temperature, 15 min) and with excellent functional group tolerance. The synthetic utility of the final products and a mechanistic rationale are also discussed.