1335053-81-0

Basic information

• Product Name: ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate
• Synonyms: ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate;ethyl 7-chloro-2-methylH-imidazo[1,2-a]pyridine-3-carboxylate
• CAS NO: 1335053-81-0
• Molecular Formula: C11H11ClN2O2
• Molecular Weight: 238.67024
• Mol File: 1335053-81-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate(1335053-81-0)
• EPA Substance Registry System: ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate(1335053-81-0)

Safety Data

• Hazardous Substances Data: 1335053-81-0(Hazardous Substances Data)

Usage

General Description

ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate is a chemical compound with a complex and specific chemical structure. It is an ester derivative of 7-chloro-2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid. ethyl 7-chloro-2-MethyliMidazo[1,2-a]pyridine-3-carboxylate is used in the pharmaceutical industry for the synthesis of various organic compounds and potentially as a precursor in the production of pharmaceutical drugs. It may also have potential applications in research and development as a building block in organic chemistry. Due to its complex structure and potential uses, ethyl 7-chloro-2-Methylimidazo[1,2-a]pyridine-3-carboxylate is a compound of interest for further study and investigation.

Upstream product

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Relevant articles and documents

Microwave assisted synthesis of disubstituted imidazo[1,2-a]pyridine-3-carboxylic acid esters

A novel and efficient synthetic method leveraging microwave-assisted organic synthesis (MAOS) to prepare disubstituted imidazo[1,2-a]- pyridine-3-carboxylic acid esters (IPCEs) (3a-z), the key intermediates for a class of novel anti-tuberculosis agents, is reported. Under microwave heating at 120 °C for 20 or 30 min, the condensations of 2-aminopyridines (1a-k) and ethyl 2-halogenated acetoacetates (2a-d) were conveniently performed in ethanol with acceptable yields.

Design, synthesis and biological activity of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides as new antitubercular agents

A series of N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides (IPAs), based on the structure of WZY02 discovered in our lab, were designed and synthesized as new anti-TB agents. Results reveal that many of them exhibit excellent in vitro inhibitory activity with low nanomolar MIC values against both drug-sensitive MTB strain H37Rv and drug-resistant clinical isolates. Compounds 15b and 15d display good safety and pharmacokinetic profiles, suggesting their promising potential to be lead compounds for future antitubercular drug discovery.