1335101-50-2

Upstream product

• 100586-27-4 ethyl (2E)-tridec-2-enoate 
• 96789-52-5 ((2R,3R)-3-decyloxiran-2-yl)methanol 
• 74962-98-4 trans-2-tridecenol 
• 112-44-7 undecylaldehyde 
• 2396-84-1 (2E,4E)-ethyl hexa-2,4-dienoate 
• 1335101-41-1 (3E,5E)-(1Ss)-(p-tolylsulfinyl)hepta-3,5-dien-2-one 
• 1335101-39-7 (3S,4S,7S,8S)-4,7-bis(benzyloxy)deca-1,9-diene-3,8-diol 
• 1335101-49-9 (1E,3S,4S,7S,8S,9E)-4,7-bis(benzyloxy)-1,10-ditosyldeca-1,9-diene-3,8-diol 
• 1335101-48-8 (5R,6S,7S,10S,11S,12R)-7,10-bis(benzyloxy)-6,11-dibromo-2,2,3,3,14,14,15,15-octamethyl-5,12-bis(tosylmethyl)-4,13-dioxa-3,14-disilahexadecane 
• 1335101-47-7 (5R,6S,7S,10S,11S,12R)-6,11-dibromo-2,2,3,3,14,14,15,15-octamethyl-5,12-bis(tosylmethyl)-4,13-dioxa-3,14-disilahexadecane-7,10-diol 
• 1335101-42-2 tert-butyldimethyl((2S,3E,5E)-(1Ss)-(p-tolylsulfinyl)hepta-3,5-dien-2-yloxy)silane 
• 1335101-40-0 (S,3E,5E)-1-((S)-p-tolylsulfinyl)hepta-3,5-dien-2-ol 

Downstream Products

• 1335101-51-3 (3S,4S,7S,8S)-4,7-bis(benzyloxy)-8-((S)-1-((R)-oxiran-2-yl)undecyloxy)deca-1,9-dien-3-ol 
• 1335101-38-6 (3R,4S)-4-((3S,4S,7S,8S)-4,7-bis(benzyloxy)-8-hydroxydeca-1,9-dien-3-yloxy)tetradec-1-en-3-ol 
• 1335101-36-4 (2S,3R,6S)-6-((1S,4S,5S)-1,4-bis(benzyloxy)-5-hydroxyhept-6-enyl)-2-decyl-3,6-dihydro-2H-pyran-3-ol 
• 1335101-53-5 ((3S,4S,7S,8S)-4,7-bis(benzyloxy)-8-((S)-1-((R)-oxiran-2-yl)undecyloxy)deca-1,9-dien-3-yloxy)triethylsilane 
• 1335101-54-6 (3R,4S)-4-((3S,4S,7S,8S)-4,7-bis(benzyloxy)-8-(triethylsilyloxy)deca-1,9-dien-3-yloxy)tetradec-1-en-3-ol 
• 1335101-55-7 (2S,3R,6S)-6-((1S,4S,5S)-1,4-bis(benzyloxy)-5-(triethylsilyloxy)hept-6-enyl)-2-decyl-3,6-dihydro-2H-pyran-3-ol 
• 1335101-56-8 ((2S,3R,6S)-6-((1S,4S,5S)-1,4-bis(benzyloxy)-5-(triethylsilyloxy)hept-6-enyl)-2-decyl-3,6-dihydro-2H-pyran-3-yloxy)(tert-butyl)dimethylsilane 

Relevant academic research and scientific papers

Toward a modular, bidirectional synthesis of (-)-mucocin

A convergent stereoselective synthesis of the C13-C34 fragment of (-)-mucocin is described. The salient features include (a) the bidirectional synthesis of the C-2 symmetric C13-C21 subunit, (b) regio- and stereoselective preparation of a 1,3-diol derivative from a diene activated by NBS via intramolecular nucleophilic sulfinyl group participation, (c) utilizing the self-metathesis reaction to prepare a functionalized C10 alkene, and (d) regio- and stereoselective intermolecular epoxide opening to construct the ether bond between C20 and C24. An organocatalytic α-hydoxylation has been employed to create the C4 stereogenic center of C1-C12 subunit. Attempted union of the two subunits utilizing the B-alkyl Suzuki coupling did not succeed.