1335136-47-4

Upstream product

• 1335136-31-6 N-[6-phenyl-5-(phenylsulfanyl)tetrahydro-2H-pyran-2-ylidene]propan-2-iminium perchlorate 
• 1335136-37-2 C₂₁H₂₅NOS*ClHO₄ 
• 1335136-19-0 C₁₄H₁₉NO 
• 1335136-21-4 C₁₅H₂₁NO 
• 931-59-9 benzenesulfenyl chloride 

Relevant academic research and scientific papers

Intramolecular electrophilic cyclization of functional derivatives of unsaturated compounds: I. synthesis of 5-arylsulfanyl-6-phenylpiperidin-2-ones from cinnamylacetamides and arylsulfenyl chlorides

Sterically nonhindered N-alkyl(aryl)amides of cinnamylacetic acid in the reaction with phenyl(4- tolyl)sulfenyl chlorides in acetic acid in the presence of lithium perchlorate undergo a selective cyclization into 5-arylsulfanyl-6- phenylpiperidin-2-ones. Under similar conditions the reaction with arylsulfenyl chlorides of amides containing bulky substituents at the nitrogen atom resulted in 5-arylsulfanyl-6-phenyltetrahydropyran-2- iminium perchlorates, which by treatment with aqueous ethanol were converted into the corresponding derivatives of pyran-2-ones.