1335143-97-9Relevant academic research and scientific papers
Merging metathesis and photochemical Csp3-H activation: Access to masked β-formyl hexanolides and their rearrangement to furofuranones
Glenadel, Quentin,Nassar, Youssef,Raffier, Ludovic,Veys, Sebastiaan,Piva, Olivier
, p. 5367 - 5373 (2018)
β-Masked formyl hexanolides were prepared by a three-step sequence including esterification of homoallylic alcohols, ring-closing metathesis and the photochemically induced addition of dioxanyl radical. When treated under oxidative conditions, the adducts underwent cleavage of the ketal group leading after rearrangement to parent furofuranones, structures found in some biological active compounds.
Synthesis and biological evaluation of α,β-unsaturated lactones as potent immunosuppressive agents
Lee, Sun-Mi,Lee, Won-Gil,Kim, Young-Chul,Ko, Hyojin
, p. 5726 - 5729 (2011/10/18)
Compounds having α,β-unsaturated lactones display a variety of biological activities. Many research groups have tested both natural and unnatural α,β-unsaturated lactones for as-yet undiscovered biological properties. We synthesized α,β-unsaturated lacton
