133523-80-5

Basic information

• Product Name: 2-Methyl-5-phenylselanylmethyl-4,5-dihydro-oxazole
• CAS NO: 133523-80-5
• Molecular Weight: 254.19
• Mol File: 133523-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Methyl-5-phenylselanylmethyl-4,5-dihydro-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-5-phenylselanylmethyl-4,5-dihydro-oxazole(133523-80-5)
• EPA Substance Registry System: 2-Methyl-5-phenylselanylmethyl-4,5-dihydro-oxazole(133523-80-5)

Safety Data

• Hazardous Substances Data: 133523-80-5(Hazardous Substances Data)

Upstream product

• 692-33-1 N-allylacetamide 
• 34837-55-3 Phenylselenyl bromide 

Relevant articles and documents

Organoselenium- and Proton-Mediated Cyclization Reactions of Allylic Amides and Thioamides. Syntheses of 2-Oxazolines and 2-Thiazolines

A variety of allylic amides and thioamides were treated with phenylselenenyl bromide in chloroform to give, via 5-exo cyclization, 2-oxazolines and 2-thiazolines, respectively, carrying a (phenylselenenyl)methyl substituent in the 5-position.In some cases (N-crotyl- and N-cinnamylamides/thioamides), dihydro-1,3-oxazines/-thiazines were formed via 6-endo cyclization.The phenylselenenyl group of the cyclofunctionalization products was slowly eliminated by treatment with m-chloroperbenzoic acid to introduce unsaturation in the resulting oxazoline/thiazoline.Reductive removal of the phenylselenenyl group was effected by treatment with triphenyltin hydride.This reaction was sometimes accompanied by a rearrangement of the heterocyclic ring.Proton-induced cyclizations of allylic thioamides to give 2-thiazolines was slowly but efficiently effected in boiling toluene containing a catalytic amount of p-toluenesulfonic acid.