1335232-85-3Relevant academic research and scientific papers
An ingenious method for the determination of the relative and absolute configurations of compounds containing aryl-glycerol fragments by1H NMR spectroscopy
Zhang, Xu,Lu, Kai-Zhou,Yan, Hai-Wei,Feng, Zi-Ming,Yang, Ya-Nan,Jiang, Jian-Shuang,Zhang, Pei-Cheng
, p. 8107 - 8116 (2021/03/03)
A concise method was established to determine the relative and absolute configurations of aryl-glycerols that depend on the chemical shift differences (Δδ) of the diastereotopic methylene protons (H-3) by1H NMR spectroscopy. When using DMSO-d6as the preferred solvent, thethreoconfiguration corresponded to a larger ΔδH3a-H3bvalue (>0.15 ppm), whereas theerythroconfiguration (a smaller value. Furthermore, the absolute configurations were determined with the aid of a simple acylation reaction through camphanoyl chloride. In thethreoenantiomers, the Δδvalue of the 1R,2Rconfiguration was 0.20 ppm. In theerythroenantiomers, the Δδvalue of 1R,2Swas >0.09 ppm, and that of 1S,2Rwas 3. In addition, this method was also verified by a quantum1H NMR calculation.
New inhibitors of colony spreading in Bacillus subtilis and Bacillus anthracis
Hao, Xin,Nguyen, Tam,Kearns, Daniel B.,Arpin, Carolynn C.,Fall, Ray,Sammakia, Tarek
supporting information; experimental part, p. 5583 - 5588 (2011/10/12)
We have recently characterized sliding motility in Bacillus subtilis strains that lack functional flagella, and here describe the discovery of inhibitors of colony spreading in these strains as well as the aflagellate pathogen, Bacillus anthracis. Aflagel
