1335304-38-5

Basic information

• Product Name: C₃₇H₄₂N₄O₈
• CAS NO: 1335304-38-5
• Molecular Weight: 670.762
• Mol File: 1335304-38-5.mol

Chemical Properties

• CAS DataBase Reference: C₃₇H₄₂N₄O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₇H₄₂N₄O₈(1335304-38-5)
• EPA Substance Registry System: C₃₇H₄₂N₄O₈(1335304-38-5)

Safety Data

• Hazardous Substances Data: 1335304-38-5(Hazardous Substances Data)

Upstream product

• 1335304-37-4 C₁₇H₂₃N₃O₇ 
• 69876-37-5 (S)-benzyl 2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoate 

Relevant articles and documents

Protection of the indole nucleus of tryptophan in solid-phase peptide synthesis with a dipeptide that can be cleaved rapidly at physiological pH

The synthesis of a new derivative of tryptophan Fmoc-Trp(Boc-Sar-Sar)-OH is described. Fmoc-Trp(Boc-Sar-Sar)-OH is introduced into peptides by solid-phase peptide synthesis and during treatment with TFA at the end of the synthesis, the Boc group is cleaved and the peptide is obtained with the indole nucleus modified with the sarcosinyl-sarcosinyl (Sar-Sar) moiety. This modification will introduce a cationic charge that improves the solubility of the peptide during HPLC purification. The Sar-Sar moiety is cleaved upon exposure to physiological pH. The Boc-Sar-Sar group might, therefore, also find use in the design of pro-drugs of indole-containing compounds.