133531-68-7

Upstream product

• 367-30-6 2,5-difluoroaniline 
• 398-90-3 (2,5-difluorophenyl)acetanilide 
• 366-53-0 N-(2,5-difluoro-4-nitrophenyl)-acetamide 
• 1542-36-5 2,5-difluoro-4-nitroaniline 

Downstream Products

• 1374780-43-4 1-[2,5-dinitro-4-(pyrrolidin-1-yl)phenyl]piperidine 
• 1374780-42-3 4-(2,5-dinitro-4-piperidin-1-ylphenyl)morpholine 
• 1374780-41-2 4,4'-(2,5-dinitro-1,4-phenylene)dimorpholine 
• 1374780-52-5 N,N'-[2,5-bis(4-oxidomorpholin-4-yl)-1,4-phenylene]diacetamide 
• 1374780-44-5 N,N'-[2,5-di(morpholin-4-yl)-1,4-phenylene]diacetamide 
• 1374780-46-7 N,N'-[2-(piperidin-1-yl)-5-(pyrrolidin-1-yl)-1,4-phenylene]diacetamide 
• 1454650-59-9 4-fluoro-2,5-dinitro-N-propyl-N-trifluoroacetylbenzeneamine 
• 1454650-60-2 N-2,5-dinitro-4-butylaminophenyl-N-propyl-2,2,2-trifluoroacetamide 
• 1454650-61-3 2-butylamino-5-propylamino-1,4-dinitrobenzene 
• 1454650-56-6 1,4-diamino-2-butylamino-5-propylamino benzene 
• 1454650-57-7 4-fluoro-2,5-dinitro-N-propylbenzeneamine 
• 1454650-58-8 N-5-dipropyl-4-fluoro-2-nitrobenzenediamine 

Relevant academic research and scientific papers

2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES

Asymmetrical 2,5-disubstituted-1,4-diaminobenzenes are provided, along with a process for forming both symmetrical and asymmetrical 2,5-disubstituted-1,4-diaminobenzenes.

Synthesis and toxicity of new ring-fused imidazo[5,4-f] benzimidazolequinones and mechanism using amine N-oxide cyclizations

A new synthetic route to ring-fused imidazo[5,4-f]benzimidazoles is reported that can be used to access symmetrical and unsymmetrical quinone anticancer agents. Oxone in formic acid allows cyclisation of o-tert-aminoacetanilides to give ring-fused benzimi