1335317-38-8Relevant articles and documents
Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors
Giroux, Simon,Xu, Jinwang,Reddy, T. Jagadeeswar,Morris, Mark,Cottrell, Kevin M.,Cadilhac, Caroline,Henderson, James A.,Nicolas, Oliver,Bilimoria, Darius,Denis, Francois,Mani, Nagraj,Ewing, Nigel,Shawgo, Rebecca,L'Heureux, Lucille,Selliah, Subajini,Chan, Laval,Chauret, Nathalie,Berlioz-Seux, Francoise,Namchuk, Mark N.,Grillot, Anne-Laure,Bennani, Youssef L.,Das, Sanjoy K.,Maxwell, John P.
, p. 240 - 243 (2016/10/17)
The discovery of potent thienoimidazole-based HCV NS5A inhibitors is herein reported. A novel method to access the thienoimidazole [5, 5]-bicyclic system is disclosed. This method gave access to a common key intermediate (6) that was engaged in Suzuki or