1335544-34-7Relevant academic research and scientific papers
Studies on the biosynthesis of the notoamides: Synthesis of an isotopomer of 6-hydroxydeoxybrevianamide e and biosynthetic incorporation into notoamide J
Finefield, Jennifer M.,Sherman, David H.,Tsukamoto, Sachiko,Williams, Robert M.
, p. 5954 - 5958 (2011)
6-Hydroxydeoxybrevianamide E is proposed as a biosynthetic precursor to several advanced metabolites isolated from both marine-derived Aspergillus sp. and a terrestrial-derived Aspergillus versicolor. To verify the role of this reverse-prenylated indole alkaloid as an intermediate along the biosynthetic pathway, [13C]2-[15N]-6- hydroxydeoxybrevianamide E was synthesized and fed to Aspergillus versicolor. Analysis of the metabolites showed incorporation of the intermediate only into the natural product notoamide J.
